Tuberin Antibody

Contact us
NSJ Bioreagents
Product Code: NSJ-F49604
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F49604-0.08ML0.08 ml£260.00
Quantity:
NSJ-F49604-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the Tuberin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
Western blot analysis of lysate from SH-SY5Y, MCF-7, PC3, LNCaP, HeLa, cell line (left to right) using Tuberin antibody at 1:1000 for each lane.
2 / 3
Fluorescent confocal image of HeLa cells stained with Tuberin antibody. Alexa Fluor 488 secondary (green) was used. Tuberin/TSC2 immunoreactivity is localized to the cytoplasm.
3 / 3
IHC analysis of FFPE human hepatocarcinoma tissue stained with Tuberin antibody
❮❯

Western blot analysis of lysate from SH-SY5Y, MCF-7, PC3, LNCaP, HeLa, cell line (left to right) using Tuberin antibody at 1:1000 for each lane.
Fluorescent confocal image of HeLa cells stained with Tuberin antibody. Alexa Fluor 488 secondary (green) was used. Tuberin/TSC2 immunoreactivity is localized to the cytoplasm.
IHC analysis of FFPE human hepatocarcinoma tissue stained with Tuberin antibody

Documents

Further Information

Application Details :
Immunofluorescence: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the Tuberin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Mutations in TSC2 lead to tuberous sclerosis complex. This protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1776-1805 from the human protein was used as the immunogen for this Tuberin antibody.
Limitation:
This Tuberin antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P49815