SOCS4 Antibody

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NSJ Bioreagents
Product Code: NSJ-F41736
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F41736-0.08ML0.08 ml£260.00
Quantity:
NSJ-F41736-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the SOCS4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from MCF-7 cell line using SOCS4 antibody diluted at 1:1000 for each lane.
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SOCS4 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue.
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Confocal immunofluorescent analysis of SOCS4 antibody with A2058 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 Phalloidin (red). DAPI was used as a nuclear counterstain (blue).
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Western blot analysis of lysate from MCF-7 cell line using SOCS4 antibody diluted at 1:1000 for each lane.
SOCS4 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue.
Confocal immunofluorescent analysis of SOCS4 antibody with A2058 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 Phalloidin (red). DAPI was used as a nuclear counterstain (blue).

Documents

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
Application Note:
Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.
Limitation:
This SOCS4 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q8WXH5