SUMO2/3 Antibody

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NSJ Bioreagents
Product Code: NSJ-F42018
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F42018-0.08ML0.08 ml£260.00
Quantity:
NSJ-F42018-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the SUMO2/3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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SUMO2/3 antibody western blot analysis in (1) 293 and (2) HeLa lysate
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Fluorescent confocal image of HeLa cell stained with SUMO2/3 antibody at 1:25. SUMO2/3 immunoreactivity is localized to the nucleus.
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IHC analysis of FFPE human hepatocarcinoma tissue stained with SUMO2/3 antibody
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SUMO2/3 antibody western blot analysis in (1) 293 and (2) HeLa lysate
Fluorescent confocal image of HeLa cell stained with SUMO2/3 antibody at 1:25. SUMO2/3 immunoreactivity is localized to the nucleus.
IHC analysis of FFPE human hepatocarcinoma tissue stained with SUMO2/3 antibody

Documents

Further Information

Application Details :
Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the SUMO2/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 53-84 from human SUMO3 was used as the immunogen for this SUMO2/3 antibody.
Limitation:
This SUMO2/3 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse, Rat, Bovine, Pig, Primate, Chicken, Zebrafish, Hamster, Xenopus
Uniprot #:
P55854