PRMT2 Antibody

NSJ Bioreagents
Product Code: NSJ-F40440
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F40440-0.08ML0.08 ml£260.00
Quantity:
NSJ-F40440-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the PRMT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC analysis of FFPE human breast carcinoma tissue stained with the PRMT2 antibody
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The PRMT2 antibody used in western blot to detect PRMT2 in HL-60 cell lysate
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Western blot analysis of PRMT2 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the PRMT2 gene.

IHC analysis of FFPE human breast carcinoma tissue stained with the PRMT2 antibody
The PRMT2 antibody used in western blot to detect PRMT2 in HL-60 cell lysate
Western blot analysis of PRMT2 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the PRMT2 gene.

Further Information

Application Details :
IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
Application Note:
Titration of the PRMT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 22-53 from the human protein was used as the immunogen for this PRMT2 antibody.
Limitation:
This PRMT2 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P55345