SUMO2 Antibody

NSJ Bioreagents
Product Code: NSJ-F42497
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F42497-0.08ML0.08 ml£260.00
Quantity:
NSJ-F42497-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the SUMO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Western blot analysis of lysate from (1) 293T, (2) HL-60, (3) Jurkat cell line using SUMO2 antibody. Observed molecular weight: 12-15 kDa.
2 / 4
Western blot analysis of SUMO2 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the SUMO2 gene.
3 / 4
Western blot using SUMO2 antibody and GST-SUMO2 fusion protein.
4 / 4
IHC analysis of FFPE human breast carcinoma tissue stained with the SUMO2 antibody

Western blot analysis of lysate from (1) 293T, (2) HL-60, (3) Jurkat cell line using SUMO2 antibody. Observed molecular weight: 12-15 kDa.
Western blot analysis of SUMO2 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the SUMO2 gene.
Western blot using SUMO2 antibody and GST-SUMO2 fusion protein.
IHC analysis of FFPE human breast carcinoma tissue stained with the SUMO2 antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the SUMO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 63-93 from the human protein was used as the immunogen for this SUMO2 antibody.
Limitation:
This SUMO2 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse, Rat, Bovine, Pig, Primate, Chicken, Zebrafish, Hamster, Xenopus
Uniprot #:
P61956