ATF6 beta Antibody
| Code | Size | Price |
|---|
| NSJ-F49022-0.08ML | 0.08 ml | £260.00 |
Quantity:
| NSJ-F49022-0.4ML | 0.4 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Hamster
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Aliquot the ATF6 beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
IHC (Paraffin): 1:25,Western blot: 1:1000
Application Note:
Titration of the ATF6 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
ATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody.
Limitation:
This ATF6 beta antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Hamster, Mouse
Uniprot #:
Q99941