DDR1 Antibody

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NSJ Bioreagents
Product Code: NSJ-F52621
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F52621-0.08ML0.08 ml£260.00
Quantity:
NSJ-F52621-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the DDR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from human brain tissue lysate using DDR1 antibody diluted at 1:1000.~
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Western blot analysis of lysate from mouse kidney tissue lysate using DDR1 antibody diluted at 1:1000. Predicted molecular weight: 1
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Western blot analysis of lysate from human brain tissue lysate using DDR1 antibody diluted at 1:1000.~
Western blot analysis of lysate from mouse kidney tissue lysate using DDR1 antibody diluted at 1:1000. Predicted molecular weight: 1

Documents

Further Information

Application Details :
Western blot: 1:500-1000
Application Note:
Titration of the DDR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This DDR1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 396-430 amino acids from the central region of human mouse Ddr1.
Limitation:
This DDR1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Species Reactivity (Predicted):
Rat
Uniprot #:
Q03146