NSJ Bioreagents

DKK1 Antibody

Product Code:
 
NSJ-F53121
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the DKK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot analysis of lysate from (1) A549, (2) HeLa, (3) HepG2, (4) Jurkat, (5) mouse NIH3T3 cell line using DKK1 antibody. Predicted molecular weight: 26-40 kDa depending on glycosylation level.~
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Western blot testing of DKK1 antib
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Western blot analysis of lysate from (1) A549, (2) HeLa, (3) HepG2, (4) Jurkat, (5) mouse NIH3T3 cell line using DKK1 antibody. Predicted molecular weight: 26-40 kDa depending on glycosylation level.~
Western blot testing of DKK1 antib

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CodeSizePrice
NSJ-F53121-0.08ML0.08 ml£260.00
Quantity:
NSJ-F53121-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000-1:4000
Application Note:
Titration of the DKK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. [UniProt]
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This DKK1 antibody was produced from a rabbit immunized with a recombinant protein of human DKK1.
Limitation:
This DKK1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Uniprot #:
O94907