WDR5 Antibody

NSJ Bioreagents
Product Code: NSJ-F52917
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F52917-0.08ML0.08 ml£260.00
Quantity:
NSJ-F52917-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the WDR5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from 1) human HeLa and 2) mouse NIH3T3 cell line using WDR5 antibody at 1:1000. Predicted molecular weight ~36 kDa.

Western blot analysis of lysate from 1) human HeLa and 2) mouse NIH3T3 cell line using WDR5 antibody at 1:1000. Predicted molecular weight ~36 kDa.

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the WDR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This WDR5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the C-terminal region of human WDR5.
Limitation:
This WDR5 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Species Reactivity (Predicted):
Rat, Bovine, Drosophila
Uniprot #:
P61964