CD105 Antibody

NSJ Bioreagents
Product Code: NSJ-F48291
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F48291-0.08ML0.08 ml£260.00
Quantity:
NSJ-F48291-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the CD105 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of CD105 antibody and mouse heart tissue lysate
2 / 4
CD105 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue.
3 / 4
Flow cytometric analysis of NCI-H292 cells using CD105 antibody (bottom histogram) compared to a negative control (top histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
4 / 4
Western blot analysis of CD105 antibody and human HeLa cell lysate. Observed molecular weight: 70/90 kDa (monomer, unmodified/glycosylated); 140-180 kDa (dimer, unmodified/glycosylated).

Western blot analysis of CD105 antibody and mouse heart tissue lysate
CD105 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue.
Flow cytometric analysis of NCI-H292 cells using CD105 antibody (bottom histogram) compared to a negative control (top histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Western blot analysis of CD105 antibody and human HeLa cell lysate. Observed molecular weight: 70/90 kDa (monomer, unmodified/glycosylated); 140-180 kDa (dimer, unmodified/glycosylated).

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
Application Note:
Titration of the CD105 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 380-409 from the human protein was used as the immunogen for this CD105 antibody.
Limitation:
This CD105 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse
Uniprot #:
P17813