ALK3 Antibody

NSJ Bioreagents
Product Code: NSJ-F47725
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F47725-0.05ML0.05 ml£260.00
Quantity:
NSJ-F47725-0.2ML0.2 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the ALK3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC analysis of FFPE human hepatocarcinoma tissue stained with the ALK3 antibody
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ALK3 western blot analysis in HeLa lysate
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Western blot testing of 1) human HEK293 and 2) mouse NIH-3T3 cell lysate with ALK3 antibody. Predicted molecular weight ~60 kDa.

IHC analysis of FFPE human hepatocarcinoma tissue stained with the ALK3 antibody
ALK3 western blot analysis in HeLa lysate
Western blot testing of 1) human HEK293 and 2) mouse NIH-3T3 cell lysate with ALK3 antibody. Predicted molecular weight ~60 kDa.

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the ALK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 166-195 from the human protein was used as the immunogen for this ALK3 antibody.
Limitation:
This ALK3 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse
Uniprot #:
P36894