SIRT3 Antibody

NSJ Bioreagents
Product Code: NSJ-F49519
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F49519-0.08ML0.08 ml£260.00
Quantity:
NSJ-F49519-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Western blot analysis of lysate from (1) 293 and (2) HepG2 cell line using SIRT3 antibody at 1:1000. Predicted size: 44/28 kDa (full/processed)
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SIRT3 antibody western blot analysis in 293 cell lysate. Predicted size: 44/28 kDa (full/processed)
3 / 4
SIRT3 antibody western blot analysis in HepG2 lysate. Predicted size: 44/28 kDa (full/processed)
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IHC analysis of FFPE human breast carcinoma tissue stained with the SIRT3 antibody

Western blot analysis of lysate from (1) 293 and (2) HepG2 cell line using SIRT3 antibody at 1:1000. Predicted size: 44/28 kDa (full/processed)
SIRT3 antibody western blot analysis in 293 cell lysate. Predicted size: 44/28 kDa (full/processed)
SIRT3 antibody western blot analysis in HepG2 lysate. Predicted size: 44/28 kDa (full/processed)
IHC analysis of FFPE human breast carcinoma tissue stained with the SIRT3 antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 250-279 from the human protein was used as the immunogen for this SIRT3 antibody.
Limitation:
This SIRT3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Uniprot #:
Q9NTG7