BACE1 Antibody

NSJ Bioreagents
Product Code: NSJ-F50758
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F50758-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50758-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store at 4oC for up to one month. For long term, aliquot the BACE1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC analysis of FFPE human brain tissue stained with BACE1 antibody~
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Western blot analysis of BACE1 antibody and mouse heart tissue lysate.

IHC analysis of FFPE human brain tissue stained with BACE1 antibody~
Western blot analysis of BACE1 antibody and mouse heart tissue lysate.

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the BACE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [UniProt]
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 38-70 from the human protein was used as the immunogen for this BACE1 antibody.
Limitation:
This BACE1 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse
Species Reactivity (Predicted):
Rat, Bovine
Uniprot #:
P56817