PINK1 Antibody

NSJ Bioreagents
Product Code: NSJ-F49623
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F49623-0.08ML0.08 ml£260.00
Quantity:
NSJ-F49623-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store at 4oC for up to one month. For long term, aliquot the PINK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from human placenta tissue, using Park6/ PINK1 antibody diluted at 1:1000. Predicted molecular weight: 60-70 kDa
2 / 3
Western blot analysis of PINK1 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the Park6/PINK1 gene.
3 / 3
IHC analysis of FFPE human hepatocarcinoma tissue stained with the PINK1 antibody

Western blot analysis of lysate from human placenta tissue, using Park6/ PINK1 antibody diluted at 1:1000. Predicted molecular weight: 60-70 kDa
Western blot analysis of PINK1 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the Park6/PINK1 gene.
IHC analysis of FFPE human hepatocarcinoma tissue stained with the PINK1 antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 118-147 from the human protein was used as the immunogen for this PINK1 antibody.
Limitation:
This PINK1 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse
Uniprot #:
Q9BXM7