SIRT3 Antibody

NSJ Bioreagents
Product Code: NSJ-F49520
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F49520-0.05ML0.05 ml£260.00
Quantity:
NSJ-F49520-0.2ML0.2 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Hamster
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store at 4oC for up to one month. For long term, aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from mouse heart tissue lysate using SIRT3 antibody diluted at 1:1000.
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Western blot analysis of SIRT3 antibody and mouse brain tissue lysate
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Western blot analysis of SIRT3 antibody and CHO lysate
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SIRT3 antibody IHC analysis in formalin fixed and paraffin embedded human breast carcinoma.

Western blot analysis of lysate from mouse heart tissue lysate using SIRT3 antibody diluted at 1:1000.
Western blot analysis of SIRT3 antibody and mouse brain tissue lysate
Western blot analysis of SIRT3 antibody and CHO lysate
SIRT3 antibody IHC analysis in formalin fixed and paraffin embedded human breast carcinoma.

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
The stated application concentrations are suggested starting points. Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
SIRT3 is an NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. [UniProt]
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 304-334 from the mouse protein was used as the immunogen for this SIRT3 antibody.
Limitation:
This SIRT3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Hamster
Uniprot #:
Q8R104