OPA1 Antibody

NSJ Bioreagents
Product Code: NSJ-F52666
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F52666-0.08ML0.08 ml£260.00
Quantity:
NSJ-F52666-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the OPA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from (1) HeLa cell line, (2) mouse brain and (3) rat brain tissue lysate using OPA1 antibody at 1:1000.

Western blot analysis of lysate from (1) HeLa cell line, (2) mouse brain and (3) rat brain tissue lysate using OPA1 antibody at 1:1000.

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the OPA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This OPA1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 895-929 amino acids from the C-terminal region of human OPA1, form S1.
Limitation:
This OPA1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Species Reactivity (Predicted):
Chicken, Zebrafish
Uniprot #:
O60313