Connexin 43 Antibody

NSJ Bioreagents
Product Code: NSJ-F44391
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F44391-0.08ML0.08 ml£260.00
Quantity:
NSJ-F44391-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the Connexin 43 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from (1) HeLa, (2) U-87 MG, (3) rat C6 cell line and (4) mouse heart tissue lysate using Connexin 43 antibody at 1:1000. Predicted molecular weight: 43 kDa
2 / 4
Western blot analysis of Connexin 43 antibody and CEM lysate
3 / 4
Western blot analysis of Connexin 43 antibody and mouse brain tissue lysate. Predicted molecular weight: 43 kDa
4 / 4
IHC analysis of FFPE human breast carcinoma tissue stained with the Connexin 43 antibody

Western blot analysis of lysate from (1) HeLa, (2) U-87 MG, (3) rat C6 cell line and (4) mouse heart tissue lysate using Connexin 43 antibody at 1:1000. Predicted molecular weight: 43 kDa
Western blot analysis of Connexin 43 antibody and CEM lysate
Western blot analysis of Connexin 43 antibody and mouse brain tissue lysate. Predicted molecular weight: 43 kDa
IHC analysis of FFPE human breast carcinoma tissue stained with the Connexin 43 antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the Connexin 43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 107-138 from the human protein was used as the immunogen for this Connexin 43 antibody.
Limitation:
This Connexin 43 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse, Rat
Species Reactivity (Predicted):
Bovine, Xenopus
Uniprot #:
P17302