SUV39H2 Antibody

Contact us
NSJ Bioreagents
Product Code: NSJ-F42488
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F42488-0.08ML0.08 ml£260.00
Quantity:
NSJ-F42488-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the SUV39H2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
Western blot analysis of lysate from 1) A431, 2) K562, 3) CEM cell line and 4) rat brain tissue using SUV39H2 antibody at 1:1000.
2 / 3
Western blot analysis of SUV39H2 antibody and 1) 293, 2) HL-60 lysate
3 / 3
IHC analysis of FFPE human breast carcinoma tissue stained with the SUV39H2 antibody
❮❯

Western blot analysis of lysate from 1) A431, 2) K562, 3) CEM cell line and 4) rat brain tissue using SUV39H2 antibody at 1:1000.
Western blot analysis of SUV39H2 antibody and 1) 293, 2) HL-60 lysate
IHC analysis of FFPE human breast carcinoma tissue stained with the SUV39H2 antibody

Documents

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the SUV39H2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 360-390 from the human protein was used as the immunogen for this SUV39H2 antibody.
Limitation:
This SUV39H2 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Rat
Species Reactivity (Predicted):
Primate
Uniprot #:
Q9H5I1