IL-23 Antibody (Center Region)
| Code | Size | Price |
|---|
| NSJ-F53999-0.05ML | 0.05 ml | £260.00 |
Quantity:
| NSJ-F53999-0.2ML | 0.2 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Aliquot the IL-23 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the IL-23 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Format :
Antigen affinity purified
Formulation :
Antibody in 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
Amino acids 33-67 from the human protein were used as the immunogen for this IL-23 antibody.
Limitation:
This IL-23 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse
Species Reactivity (Predicted):
Human
Uniprot #:
Q9NPF7