Phospho-TSC1 Antibody (pS312)

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NSJ Bioreagents
Product Code: NSJ-F48784
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F48784-0.08ML0.08 ml£260.00
Quantity:
NSJ-F48784-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Applications:
  • Dot Blot
  • Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot the phospho-TSC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Dot blot analysis of phospho-TSC1 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
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Dot blot analysis of phospho-TSC1 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

Documents

Further Information

Application Details :
Dot blot: 1:500
Application Note:
Titration of the phospho-TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS312 of rat TSC1.
Limitation:
This phospho-TSC1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Rat
Uniprot #:
Q9Z136