Bad Antibody

NSJ Bioreagents
Product Code: NSJ-F42760
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F42760-0.08ML0.08 ml£260.00
Quantity:
NSJ-F42760-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the Bad antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of Bad antibody and HL-60 lysate. Predicted molecular weight: 19-23 kDa~
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IHC analysis of FFPE human lung carcinoma tissue stained with Bad antibody

Western blot analysis of Bad antibody and HL-60 lysate. Predicted molecular weight: 19-23 kDa~
IHC analysis of FFPE human lung carcinoma tissue stained with Bad antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the Bad antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 53-81 from the human protein was used as the immunogen for this Bad antibody.
Limitation:
This Bad antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q92934