HIPPI Antibody
| Code | Size | Price |
|---|
| NSJ-F54213-0.05ML | 0.05 ml | £260.00 |
Quantity:
| NSJ-F54213-0.2ML | 0.2 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the HIPPI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western Blot: 1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the HIPPI antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 159-193 from the human protein was used as the immunogen for the HIPPI antibody.
Limitation:
This HIPPI antibody is available for research use only.
Purity:
Peptide affinity purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Bovine
Uniprot #:
Q9NWB7