KCNH1 Antibody (C-Terminal Region)

WB: 1:1000-1:2000

The stated application concentrations are suggested starting points. Titration of the KCNH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. Potassium voltage-gated channel subfamily H member 1 is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [Wiki]

Antigen affinity purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

A portion of amino acids 787-820 from human Potassium voltage-gated channel subfamily H member 1 protein was used as the immunogen for the KCNH1 antibody.

This KCNH1 antibody is available for research use only.

Antigen affinity

Human

O95259