KLK6 Antibody / Kallikrein 6

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NSJ Bioreagents
Product Code: NSJ-F54850
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54850-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54850-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the KLK6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of human lung tissue lysate with KLK6 antibody. Predicted molecular weight ~27 kDa.
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Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with KLK6 antibody.
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IHC testing of FFPE human breast carcinoma tissue with KLK6 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
4 / 4
Flow cytometry testing of human HEK293 cells with KLK6 antibody; Blue=isotype control, Green= KLK6 antibody.
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Western blot testing of human lung tissue lysate with KLK6 antibody. Predicted molecular weight ~27 kDa.
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with KLK6 antibody.
IHC testing of FFPE human breast carcinoma tissue with KLK6 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Flow cytometry testing of human HEK293 cells with KLK6 antibody; Blue=isotype control, Green= KLK6 antibody.

Documents

Further Information

Application Details :
Western blot: 1:1000-1:2000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:10-1:50
Application Note:
The stated application concentrations are suggested starting points. Titration of the KLK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1-30 from the human protein was used as the immunogen for the KLK6 antibody.
Limitation:
This KLK6 antibody is available for research use only.
Localization:
Cytoplasmic, nuclear, secreted
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
Q92876