FGG Antibody / Fibrinogen gamma chain / FIBG

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NSJ Bioreagents
Product Code: NSJ-F54860
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54860-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54860-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the FGG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC testing of FFPE human skeletal muscle tissue with FGG antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
2 / 4
Immunofluorescent staining of human MDA-MB-231 cells with FGG antibody (green) and DAPI nuclear stain (blue).
3 / 4
Western blot testing of human A431 cell lysate with FGG antibody. Predicted molecular weight ~52 kDa.
4 / 4
Western blot testing of human NIC-H460 cell lysate with FGG antibody. Predicted molecular weight ~52 kDa.
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IHC testing of FFPE human skeletal muscle tissue with FGG antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Immunofluorescent staining of human MDA-MB-231 cells with FGG antibody (green) and DAPI nuclear stain (blue).
Western blot testing of human A431 cell lysate with FGG antibody. Predicted molecular weight ~52 kDa.
Western blot testing of human NIC-H460 cell lysate with FGG antibody. Predicted molecular weight ~52 kDa.

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:500-1:1000
Application Note:
The stated application concentrations are suggested starting points. Titration of the FGG antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 420-449 from the human protein was used as the immunogen for the FGG antibody.
Limitation:
This FGG antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P02679