ALDH5A1 Antibody

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NSJ Bioreagents
Product Code: NSJ-F54698
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54698-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54698-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the ALDH5A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with ALDH5A1 antibody. Predicted molecular weight ~57 kDa.
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Western blot testing of human liver lysate with ALDH5A1 antibody. Predicted molecular weight ~57 kDa.
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IHC testing of FFPE human hepatocarcinoma tissue with ALDH5A1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with ALDH5A1 antibody. Predicted molecular weight ~57 kDa.
Western blot testing of human liver lysate with ALDH5A1 antibody. Predicted molecular weight ~57 kDa.
IHC testing of FFPE human hepatocarcinoma tissue with ALDH5A1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the ALDH5A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 128-157 from the human protein was used as the immunogen for the ALDH5A1 antibody.
Limitation:
This ALDH5A1 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Antigen affinity purified
Species Reactivity :
Human
Uniprot #:
P51649