Collagenase 3 Antibody / MMP13
Code | Size | Price |
---|
NSJ-F54843-0.08ML | 0.08 ml | £260.00 |
Quantity:
NSJ-F54843-0.4ML | 0.4 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Aliquot the Collagenase 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Images
Documents
Further Information
Application Details :
Immunohistochemistry (FFPE): 1:50-1:100, Western blot: 1:500-1:1000
Application Note:
The stated application concentrations are suggested starting points. Titration of the Collagenase 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 295-324 from the human protein was used as the immunogen for the Collagenase 3 antibody.
Limitation:
This Collagenase 3 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P45452