MEAK7 Antibody / TLDC1 / KIAA1609

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NSJ Bioreagents
Product Code: NSJ-F54549
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54549-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54549-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the MEAK7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
IHC testing of FFPE human uterus tissue with MEAK7 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
2 / 4
Western blot testing of human DU145 cell lysate with MEAK7 antibody. Predicted molecular weight ~51 kDa.
3 / 4
Western blot testing of mouse NIH 3T3 cell lysate with MEAK7 antibody. Predicted molecular weight ~51 kDa.
4 / 4
Flow cytometry testing of mouse NIH 3T3 cells with MEAK7 antibody; Blue=isotype control, Green= MEAK7 antibody.
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IHC testing of FFPE human uterus tissue with MEAK7 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of human DU145 cell lysate with MEAK7 antibody. Predicted molecular weight ~51 kDa.
Western blot testing of mouse NIH 3T3 cell lysate with MEAK7 antibody. Predicted molecular weight ~51 kDa.
Flow cytometry testing of mouse NIH 3T3 cells with MEAK7 antibody; Blue=isotype control, Green= MEAK7 antibody.

Documents

Further Information

Application Details :
Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000, Immunohistochemistry (FFPE): 1:25
Application Note:
The stated application concentrations are suggested starting points. Titration of the MEAK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome. [UniProt]
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 426-456 from the human protein was used as the immunogen for the MEAK7 antibody .
Limitation:
This MEAK7 antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse
Uniprot #:
Q6P9B6