Lingo1 Antibody

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NSJ Bioreagents
Product Code: NSJ-F54318
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54318-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54318-0.4ML0.4 ml£469.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the Lingo1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC testing of FFPE human brain tissue with Lingo1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
2 / 3
IHC testing of FFPE human brain tissue with Lingo1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
3 / 3
Western blot testing of mouse 1) brain and 2) cerebellum lysate with Lingo1 antibody. Expected molecular weight: 69-83 kDa depending on glycosylation level.
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IHC testing of FFPE human brain tissue with Lingo1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
IHC testing of FFPE human brain tissue with Lingo1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of mouse 1) brain and 2) cerebellum lysate with Lingo1 antibody. Expected molecular weight: 69-83 kDa depending on glycosylation level.

Documents

Further Information

Application Details :
Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:25
Application Note:
The stated application concentrations are suggested starting points. Titration of the Lingo1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
'Leucine-rich repeat and immunoglobulin domain-containing protein 1' is the functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. [UniProt]
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 575-603 from the mouse protein was used as the immunogen for the Lingo1 Antibody.
Limitation:
This Lingo1 antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse
Uniprot #:
Q9D1T0