ACVR1 Antibody / ALK2

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NSJ Bioreagents
Product Code: NSJ-F54674
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54674-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54674-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the ALK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of mouse bladder tissue lysate with ALK2 antibody. Predicted molecular weight ~57 kDa.
2 / 4
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with ALK2 antibody. Predicted molecular weight ~57 kDa.
3 / 4
Western blot testing of human HeLa cell lysate with ALK2 antibody. Predicted molecular weight ~57 kDa.
4 / 4
IHC testing of FFPE mouse skeletal muscle tissue with ALK2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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Western blot testing of mouse bladder tissue lysate with ALK2 antibody. Predicted molecular weight ~57 kDa.
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with ALK2 antibody. Predicted molecular weight ~57 kDa.
Western blot testing of human HeLa cell lysate with ALK2 antibody. Predicted molecular weight ~57 kDa.
IHC testing of FFPE mouse skeletal muscle tissue with ALK2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the ALK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 137-166 from the mouse protein was used as the immunogen for the ALK2 antibody.
Limitation:
This ALK2 antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse
Uniprot #:
P37172