Survivin Antibody / BIRC5
| Code | Size | Price |
|---|
| NSJ-N1087-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1087-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 2-5ug/ml
Application Note:
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
Survivin, also called BIRC5, is a protein encoded by the human BIRC5 gene. It is a member of the IAP (inhibitor of apoptosis family. Survivin binds to the active form of Caspase-3 and -7, effector or executioner caspases, preventing them from continuing the apoptosis-signaling cascade. Expression is regulated by p53, a regulator of apoptosis-control genes which interacts with the Survivin gene promoter region to repress its expression at the mRNA and protein level.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
332
Immunogen:
A recombinant protein fragment from human Survivin was used as the immunogen for this antibody.
Limitation:
This Survivin antibody is available for research use only.
Purity:
Protein A affinity chromatography
Species Reactivity :
Human