DUSP1 Antibody

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NSJ Bioreagents
Product Code: NSJ-RQ6126
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6126-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
After reconstitution, the DUSP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Images

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Flow cytometry testing of human Caco-2 cells with DUSP1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= DUSP1 antibody.
2 / 2
Western blot testing of human 1) U-87 MG, 2) HeLa and 3) A549 cell lysate with DUSP1 antibody. Predicted molecular weight ~39 kDa.
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Flow cytometry testing of human Caco-2 cells with DUSP1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= DUSP1 antibody.
Western blot testing of human 1) U-87 MG, 2) HeLa and 3) A549 cell lysate with DUSP1 antibody. Predicted molecular weight ~39 kDa.

Documents

Further Information

Application Details :
Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells
Application Note:
Optimal dilution of the DUSP1 antibody should be determined by the researcher.
Description:
Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene. The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids NAELRGRLLAGAYHAVVLLDERSAALD from the human protein were used as the immunogen for the DUSP1 antibody.
Limitation:
This DUSP1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P28562