ATG4B Antibody
| Code | Size | Price |
|---|
| NSJ-N1210-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1210-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Aliquot the ATG4B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 4-8ug/ml
Application Note:
Provided assay concentrations are suggestions only, ATG4B antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The ?autophagy-related gene? ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
23192
Immunogen:
A recombinant protein fragment from the C-terminal region of ATG4B was used as the immunogen for this antibody.
Limitation:
This ATG4B antibody is available for research use only.
Purity:
Protein A affinity chromatography
Species Reactivity :
Human, Mouse