EDG1 Antibody
| Code | Size | Price |
|---|
| NSJ-N1039-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1039-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Aliquot the EDG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 4-6ug/ml
Application Note:
Provided assay concentrations are suggestions only, EDG1 antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
1901
Immunogen:
A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.
Limitation:
This EDG1 antibody is available for research use only.
Purity:
Protein A affinity chromatography
Species Reactivity :
Human, Mouse, Rat