GBL Antibody
| Code | Size | Price |
|---|
| NSJ-N1215-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1215-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Aliquot the GBL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 1-3ug/ml
Application Note:
Provided assay concentrations are suggestions only, GBL antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
GBL (G protein beta subunit-like), also called MLST8 (MTOR associated protein, LST8 homolog), is a subunit of the mTOR signaling complexes mTORC1 and mTORC2, which help regulate cell growth and survival in response to growth factor (mTORC1 & 2) and nutrient (mTORC1) signaling. It is required for the phosphorylation of S6 kinase and the signal adaptor protein Insulin receptor substrate 1 and S473 phosphorylation of AKT. GBL is also a regulator of TNFa-induced NF-kB activity, with overexpression inhibiting and down-regulation enhancing NF-kB signaling (Kim et al, 2008).
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
64223
Immunogen:
A recombinant protein fragment from the internal region of human GBL was used as the immunogen for this antibody.
Limitation:
This GBL antibody is available for research use only.
Purity:
Protein A affinity chromatography
Species Reactivity :
Human, Mouse, Rat