TMPRSS3 Antibody

Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Optimal dilution of the TMPRSS3 antibody should be determined by the researcher.

Transmembrane protease, serine 3 is an enzyme that in humans is encoded by the TMPRSS3 gene. This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

A human recombinant partial protein (amino acids E3-T454) was used as the immunogen for the TMPRSS3 antibody.

This TMPRSS3 antibody is available for research use only.

Affinity purified

Human, Mouse, Rat

P57727