UPK1B Antibody / Uroplakin 1B

Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml

Optimal dilution of the UPK1B antibody should be determined by the researcher.

Lyophilized from 1X PBS with 2% Trehalose

Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.

Purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Recombinant human protein (amino acids I107-Q216) was used as the immunogen for the UPK1B antibody.

This UPK1B antibody is available for research use only.

Antigen affinity purified

Human, Mouse, Rat

O75841