Aigp1 Antibody / Serinc3

NSJ Bioreagents
Product Code: NSJ-RQ6363
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6363-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
After reconstitution, the Aigp1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Images

1 / 3
Immunofluorescent staining of FFPE mouse HEPA1-6 cells with Aigp1 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
2 / 3
Western blot testing of 1) rat liver, 2) rat kidney and 3) mouse liver lysate with Aigp1 antibody. Predicted molecular weight ~53 kDa.
3 / 3
Flow cytometry testing of mouse RAW264.7 cells with Aigp1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Aigp1 antibody.

Immunofluorescent staining of FFPE mouse HEPA1-6 cells with Aigp1 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of 1) rat liver, 2) rat kidney and 3) mouse liver lysate with Aigp1 antibody. Predicted molecular weight ~53 kDa.
Flow cytometry testing of mouse RAW264.7 cells with Aigp1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Aigp1 antibody.

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Aigp1 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Serine incorporator 3 / Axotomy-induced glycoprotein 1 is a protein that in humans is encoded by the SERINC3 gene. Also found on the membranes of the Golgi apparatus within cells, Axotomy-induced glycoprotein 1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates Axotomy-induced glycoprotein 1 as being involved in the cellular transformation from normal to malignant tissue. It is believed it contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis.
Format :
Purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant mouse protein (amino acids E59-Y404) was used as the immunogen for the Aigp1 antibody.
Limitation:
This Aigp1 antibody is available for research use only.
Localization:
Cytoplasmic, cell membrane
Purity:
Antigen affinity purified
Species Reactivity :
Mouse, Rat
Uniprot #:
Q9QZI9