SIN1 Antibody
| Code | Size | Price |
|---|
| NSJ-N1067-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1067-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Aliquot and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 1-3ug/ml
Application Note:
Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
79109
Immunogen:
A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
Limitation:
This SIN1 antibody is available for research use only.
Purity:
Protein A purified antibody
Species Reactivity :
Human, Mouse, Rat, Dog