anti-p70S6K (human) Rabbit Monoclonal (RM438)

RevMab Biosciences
Product Code: REV-31-1329-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1329-00-R100100 ul£455.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM438
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
BLUE ICE
Storage:
Long Term: -20°C

Images

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Further Information

Alternate Names/Synonyms:
Ribosomal Protein S6 Kinase
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the N-terminus of p70S6K.
Long Description:
Recombinant Antibody. This antibody reacts to human p70S6K. Apllication: IHC, WB. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The p70S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70S6 kinase is predominantly localized in the cytoplasm and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response and tissue repair. p70S6 kinase acts downstream of phosphoinositide (PI) 3-kinase and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70S6 kinase leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding p70S6 kinase and overexpression are seen in some breast cancer cell lines.
NCBI, Uniprot Number:
P23443
Package Type:
Vial
Product Description:
The p70S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70S6 kinase is predominantly localized in the cytoplasm and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response and tissue repair. p70S6 kinase acts downstream of phosphoinositide (PI) 3-kinase and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70S6 kinase leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding p70S6 kinase and overexpression are seen in some breast cancer cell lines.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human p70S6K.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.