anti-HDAC3 (human) Rabbit Monoclonal (RM439)

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RevMab Biosciences
Product Code: REV-31-1330-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1330-00-R100100 ul£455.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM439
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
BLUE ICE
Storage:
Long Term: -20°C

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Further Information

Alternate Names/Synonyms:
Histone Deacetylase 3; RPD3-2; SMAP45
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the C-terminus of HDAC3.
Long Description:
Recombinant Antibody. This antibody reacts to human HDAC3. Apllication: IHC, WB. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. HDAC3 is a histone deacetylase and is responsible for the deacetylation of lysine residues on core histones and other histone substrates. The deacetylation of histones is important for transcriptional regulation, cell cycle progression and other developmental related functions. HDAC3 represses gene expression by participating in the transcriptional repressor activity of BCL6, by deacetylating H3K27 on enhancer elements. It is also thought to participate in transcriptional regulation through binding to YY1, a zinc-finger transcription factor. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. The HDAC3 gene is regarded as a potential tumor suppressor gene.
NCBI, Uniprot Number:
O15379
Package Type:
Vial
Product Description:
HDAC3 is a histone deacetylase and is responsible for the deacetylation of lysine residues on core histones and other histone substrates. The deacetylation of histones is important for transcriptional regulation, cell cycle progression and other developmental related functions. HDAC3 represses gene expression by participating in the transcriptional repressor activity of BCL6, by deacetylating H3K27 on enhancer elements. It is also thought to participate in transcriptional regulation through binding to YY1, a zinc-finger transcription factor. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. The HDAC3 gene is regarded as a potential tumor suppressor gene.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human HDAC3.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.