anti-ANO1 [TMEM16A] (human) Rabbit Monoclonal (RM440)
| Code | Size | Price |
|---|
| REV-31-1331-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM440
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
BLUE ICE
Storage:
Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
Anoctamin-1; DOG1
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the internal region of human ANO1.
Long Description:
Recombinant Antibody. This antibody reacts to human ANO1. Apllication: IHC. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. ANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. ANO1 acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Its overexpression was reported in esophageal squamous cell carcinoma and breast cancer progression.
NCBI, Uniprot Number:
Q5XXA6
Package Type:
Vial
Product Description:
ANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. ANO1 acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Its overexpression was reported in esophageal squamous cell carcinoma and breast cancer progression.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human ANO1.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.