KTSAVLQ-Rhodamine110-gamma-Glu
| Code | Size | Price |
|---|
| SBB-PS0130-C250 | 250 ug | £561.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
BLUE ICE
Storage:
Short Term Storage: +4?C. Long Term Storage: -20?C
Documents
Further Information
Alternate Names/Synonyms:
Lys-Tyr-Ser-Ala-Val-Leu-Glu-Rhodamine110-gamma-Glu
Appearance:
Lyophilized powder.
EClass:
32160000
Form (Short):
solid
Handling Advice:
Avoid freeze/thaw cycles. Protect from light. Protect from light when in solution.
Long Description:
Chemical. Molecular Weight: 1187.3. KTSAVLQ-Rhodamine110-y-Glu (Lys-Tyr-SerAla-Val-Leu-Glu-Rh110-y-Glu) is a Rhodamine110 labeled fluorogenic peptidyl substrate that can be hydrolyzed by 3CLpro (Mpro) (#SBB-DE0129) a chemotrypsin-like protease, cleaving between the glutamine and the Rhodamine110 fluorophore. Prior hydrolysis, the Rhodamine110 moiety is quenched resulting in a very low background. This substrate is ideal for activity determination of 3CLpro and suitable for HTS or pilot screens in search for potential inhibitors due to its red-shifted fluorescence compared to AMC or Dabcyl/Edans substrates. This results in less interference with potential inhibitors in screeing campaigns. Ex/Em=485nm/535nm (recommended).
Molecular Weight:
1187.3
Package Type:
Plastic Vial
Product Description:
KTSAVLQ-Rhodamine110-y-Glu (Lys-Tyr-SerAla-Val-Leu-Glu-Rh110-y-Glu) is a Rhodamine110 labeled fluorogenic peptidyl substrate that can be hydrolyzed by 3CLpro (Mpro) (#SBB-DE0129) a chemotrypsin-like protease, cleaving between the glutamine and the Rhodamine110 fluorophore. Prior hydrolysis, the Rhodamine110 moiety is quenched resulting in a very low background. This substrate is ideal for activity determination of 3CLpro and suitable for HTS or pilot screens in search for potential inhibitors due to its red-shifted fluorescence compared to AMC or Dabcyl/Edans substrates. This results in less interference with potential inhibitors in screeing campaigns. Ex/Em=485nm/535nm (recommended).
Purity:
>99% (HPLC)
Sequence:
Lys-Tyr-Ser-Ala-Val-Leu-Glu-Rhodamine110-gamma-Glu
Solubility Chemicals:
Soluble in physiological aqueous buffer.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.