S-Nitrosoglutathione
| Code | Size | Price |
|---|
| CDX-N0262-M010 | 10 mg | £48.00 |
Quantity:
| CDX-N0262-M050 | 50 mg | £157.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term Storage: +4?C. Long Term Storage: -20?C
Documents
Further Information
Alternate Names/Synonyms:
GSNO; SNOG
Appearance:
Pale pink powder.
CAS:
57564-91-7
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1
InChiKey:
HYHSBSXUHZOYLX-WDSKDSINSA-N
Long Description:
Chemical. CAS: 57564-91-7. Formula: C10H16N4O7S. Molecular Weight: 336.32. S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content.
MDL:
MFCD00214341
Molecular Formula:
C10H16N4O7S
Molecular Weight:
336.32
Package Type:
Vial
Product Description:
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content.
Purity:
>97% (NMR)
SMILES:
OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSN=O)=O)=O
Solubility Chemicals:
Soluble in water (20 mg/ml) or DMSO (20mg/ml).
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20?C.
References
(1) M.W. Radomski, et al.; Br. J. Pharmacol. 107, 745 (1992) | (2) W.R. Mathews & S.W. Kerr; J. Pharmacol. Exp. Ther. 267, 1529 (1993) | (1) E.A. Konorev, et al.; J. Pharmacol. Exp. Ther. 274, 200 (1995) | (4) A. Gasco, et al.; Farmaco 51, 617 (1996) | (5) J.A. Cook, et al.; Anal. Biochem. 238, 150 (1996) | (6) A.R. Butler & P. Rhodes; Anal. Biochem. 249, 1 (1997) | (7) R. Motterlini, et al.; J. Biol. Chem. 275, 13613 (2000) | (8) H. K. Jeon, et al.; Cell. Biol. Toxicol. 21, 115 (2005) | (9) C.X. Yu, et al.; Mol. Pharmacol. 68, 847 (2005) | (10) M. Khan, et. al.; J. Cereb. Blood Flow Metab. 25, 177 (2005) | (11) D. McGrowder, et al.; J. Biosci. 31, 347 (2006) | (12) R. Prasad, et al.; Glia 55, 65 (2007) | (13) M. Mussbacher, et al.; Sci. Rep. 9, 15403 (2019)