Certolizumab Antibody, Monoclonal
| Code | Size | Price |
|---|
| PSI-21-855-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: Fab-IgG1
Antibody Clonality: Recombinant Antibody
Regulatory Status: RUO
Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4?C short term (1-2 weeks).
Store at -20 ?C 12 months.
Store at -80?C long term.
Documents
Further Information
Additional Names:
DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Background:
Tumor necrosis factor alpha (TNF?) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNF? is in the regulation of immune cells. TNF? is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF? production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNF? is used as an immunostimulant under the INN tasonermin. TNF? can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
Buffer:
PBS buffer pH 7.5
Concentration:
batch dependent
Conjugate:
Unconjugated
NCBI Gene ID #:
7124
NCBI Official Name:
tumor necrosis factor
NCBI Official Symbol:
TNF
NCBI Organism:
Homo sapiens
Protein Accession #:
P01375
Purification:
>95%
Purity:
>95%
Research Area:
Drug Analogues
Source:
CHO cells
Swissprot #:
P01375
User NOte:
For research use only .