Brentuximab Antibody, Monoclonal
| Code | Size | Price |
|---|
| PSI-21-857-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: Human IgG1
Antibody Clonality: Recombinant Antibody
Regulatory Status: RUO
Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4?C short term (1-2 weeks).
Store at -20 ?C 12 months.
Store at -80?C long term.
Documents
Further Information
Additional Names:
CD30; Ki-1; D1S166E
Background:
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Buffer:
PBS buffer pH 7.5
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Humanized / TNFRSF8 (CD30, D1S166E, Ki-1) [Homo sapiens]
NCBI Gene ID #:
943
NCBI Official Name:
TNF receptor superfamily member 8
NCBI Official Symbol:
TNFRSF8
NCBI Organism:
Homo sapiens
Protein Accession #:
P28908
Purification:
>95%
Purity:
>95%
Research Area:
Drug Analogues
Source:
CHO cells
Swissprot #:
P28908
User NOte:
For research use only .