Moxetumomab Antibody, Monoclonal
| Code | Size | Price |
|---|
| PSI-21-866-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Clonality: Recombinant Antibody
Regulatory Status: RUO
Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4?C short term (1-2 weeks).
Store at -20 ?C 12 months.
Store at -80?C long term.
Documents
Further Information
Additional Names:
SIGLEC2; SIGLEC-2
Background:
B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Buffer:
PBS buffer pH 7.5
Concentration:
batch dependent
Conjugate:
Unconjugated
NCBI Gene ID #:
933
NCBI Official Name:
CD22 molecule
NCBI Official Symbol:
CD22
NCBI Organism:
Homo sapiens
Protein Accession #:
P20273
Purification:
>95%
Purity:
>95%
Research Area:
Drug Analogues
Source:
CHO cells
Swissprot #:
P20273
User NOte:
For research use only .