SARS-CoV-2 (COVID-19) Omicron Variant (B.1.1.529) Spike RBD Recombinant Protein
| Code | Size | Price |
|---|
| PSI-21-844-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: SARS-CoV-2
Application: Immunogen
Storage:
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for one week . Store at -20 to -80 ˚C for twelve months from the date of receipt.
Documents
Further Information
Additional Names:
S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, Delta variant spike RBD
Application Note:
Immunogen
Background:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological
processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known
receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of
coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most
notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike
(S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen
and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through
interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits,
S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizingantibody
and T-cell responses, as well as protective immunity.
Buffer:
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
43740578
NCBI Official Name:
Surface glycoprotein
NCBI Official Symbol:
S
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Lyophilized
Predicted Molecular Weight:
53.21 kDa
Protein Accession #:
UFO69279.1
Purity:
>90% as determined by SDS-PAGE
Recombinant Protein Sequence:
#N/A
Source:
Mammalian Cells
Swissprot #:
P0DTC1