SARS-CoV-2 (COVID-19) Delta Variant Spike RBD (His-Avi Tag) Recombinant Protein

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ProSci
Product Code: PSI-95-126
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-95-126-0.05mg0.05mg£347.00
Quantity:
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Overview

Host Type: Human
Regulatory Status: RUO
Target Species: SARS-CoV-2
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • SDS-PAGE
  • Western Blot (WB)
Shipping:
Dry Ice
Storage:
Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Documents

Further Information

Additional Names:
S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, Delta variant spike RBD
Application Note:
This recombinant protein can be used for WB and ELISA. For research use only.
Background:
SARS-CoV-2 delta variant, a variant of concern (VOC), known as B.1.617.2, was detected in India in October of 2020. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 99% of the cases. This variant carries at least 13 mutations in spike protein across the sub lineages, including L452R, D614G, P681R and K417N, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Delta variant was observed globally, which is at least 2.5 times more contagious as the other variants. The Delta variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent.
Background References:
  • Zhang et al. JAMA 2021, 325 (13): 1324-26.
  • Reardon. Nature 2021.
  • Delphine. Nature 2021, 596 (7871): 276-280.
Buffer:
PBS (pH 7.4).
Fusion Tag:
His-Avi tag at C-terminus
NCBI Gene ID #:
43740578
NCBI Official Name:
Surface glycoprotein
NCBI Official Symbol:
S
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Predicted Molecular Weight:
35 kD
Protein Accession #:
QHD43416.1
Purity:
> 95% as determined by Bis-Tris PAGE
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P0DTC1