ProSci

PGAM5 (CT) Peptide

Product Code:
 
PSI-9517P
Product Group:
 
Peptides
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Blocking
Storage:
 
Store PGAM5 (CT) Peptide at -20˚C, stable for one year.
 

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CodeSizePrice
PSI-9517P-0.05mg0.05mg£166.00
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Further Information

Additional Names:
Serine/threonine-protein phosphatase PGAM5 mitochondrial, Bcl-XL-binding protein v68, Phosphoglycerate mutase family member 5
Application Note:
PGAM5 (CT) Peptideis used for blocking the activity of thePGAM5 (CT) Antibody
Background:
PGAM5 Antibody: PGAM5 is a central mediator for programmed necrosis induced by TNF and may be a regulator of mitochondrial dynamics. It displays phosphatase activity for serine/threonine residues, dephosphorylates and activates MAP3K5 kinase. It has apparently no phosphoglycerate mutase activity and is a substrate for a KEAP1-dependent ubiquitin ligase complex. It is also contributes to the repression of NFE2L2-dependent gene expression
Background References:
  • Lo S. et al. Exp. Cell Res. 2018; 314(8): 1789-1803
  • Takeda et al. PNAS 2009; 106(30): 12301-12305
  • Want et al. Cell 2012; 148(1-2); 228-243
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
NCBI Gene ID #:
192111
NCBI Official Name:
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
NCBI Official Symbol:
PGAM5
NCBI Organism:
Homo sapiens
Peptide aa Location:
14 amino acids near the carboxy terminus of PGAM5 (CT).
Physical State:
Liquid
Protein Accession #:
Q96HS1
Protein GI Number:
150417955
Swissprot #:
Q96HS1
User Note:
Optimal dilutions for each application to be determined by the researcher.

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